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![]() ![]() In the non-TNBC group, receiving neoadjuvant CT (P=0.001), being ≥70 years old (P<0.001), being postmenopausal (P=0.002), having a grade 2-3 disease (p=0.026), having the T3-4 disease (P<0.001), the having N2-3 disease (P<0.001), the presence of ECE (P<0.001), the presence of LVI (P<0.001), the presence of metastasis (P<0.001), the presence of brain (P<0.001) and visceral (P=0.014) metastasis and the presence of local regional recurrence (P=0.021) were found to have a negative effect on OS (Table 4). No effect on DFS was found while f a c t o r s l i ke being ≥70 years of age (P=0.05), having t he T3-4 disease (P=0.040), the presence of PNI (P=0.022), the presence of metastasis (P<0.001), and the presence of brain metastasis (P=0.049) had a negative effect on OS in univariate analysis in the TNBC group (Table 4). Receiving neoadjuvant CT (P=0.017), having the N2-3 disease (P=0.026), and the presence of ECE (P=0.049) had a negative effect on DFS. 2 Triple negative breast cancer (TNBC) consists of subgroups in which estrogen receptor (ER) and progesterone receptor (PR) stain less than 20 (P=0.014), having the T3-4 disease (P<0.001), having the N2-3 disease (P<0.001), the presence of ECE (P<0.001), the presence of PNI (P=0.014), the presence of LVI (P<0.001), the presence of metastasis (P<0.001), the presence of brain (P<0.001) and visceral (P=0.011) metastasis and the presence of local regional recurrence (P=0.004) were found to have a negative effect on OS in univariate analyses. 1 Breast cancer is a heterogeneous disease and is divided into 4 molecular groups: Luminal A, Luminal B, human epidermal growth factor receptor-2 (HER-2) positive and triple negative subtypes according to hormone receptor status. ![]() Since hormonal treatment cannot be used in this group, individualization of treatments gains importance by knowing the prognostic factors.īreast cancer (BC) is the most common type of cancer in women in the world, and it is the 2 nd most common cause of cancer-related deaths. In the TNBC group, being ≥70 years of age (p=0.05), having T3-4 disease (p=0.040), presence of PNI (p=0.022), presence of metastasis (p<0.001), presence of brain metastasis (p=0.049) had a negative effect on OS in univariate analysis.Ĭonclusion: Shorter OS and DFS were found in the TNBC group similar to previous studies. Brain metastasis was observed more frequently in the TNBC group. It was not statistically significant as well as local recurrence was higher in the TNBC group. Disease-free survival (DFS) was median 29.7 months in the TNBC group and 52.37 months in the non-TNBC group. Results: 110(11.1%) of 992 patients were triple negative. Survival rates were evaluated using Kaplan Meirer method. ![]() Clinicopathological and treatment parameters of both groups were compared. Methods: The patients were divided into two groups as TNBC and non-TNBC. Determining the prognostic factors and parameters affecting survival in the TNBC group were aimed with this retrospective study. Background: Triple negative breast cancer (TNBC) is the most aggressive and worst prognosis group among breast cancer molecular subtypes. ![]() ![]() ![]() The parties might well commission surveys and make lots of other arguments about the connection in the public’s mind between red soles and Louboutin. Patent and Trademark Office for “a lacquered red sole” on “women’s high fashion designer footwear,” which means a court will presume its validity. Plus, Louboutin secured a registration from the U.S. All the friends in my informal poll recognized the red soles as a unique Louboutin feature (and not just from reading a recent Lauren Collins New Yorker profile that called them “a marketing gimmick that renders an otherwise indistinguishable product instantly recognizable”). U.P.S.’ brown trucks and Owens-Corning’s pink insulation both enjoy trademark protection.īut the Court also noted that competitors may still copy colors if they are “functional”-that is, if they are important to the way a product works beyond merely the reputation they bestow.įor Louboutin to prevail, then, it will have to show three things: that consumers associate the red sole with Louboutin shoes (that’s where his celebrity clients come in) that they might be confused by an imitator and that the red soles are not “functional”-which is to say, the basic function of a competing product isn’t hampered by not copying the color. A color, according to the ruling, may serve as a trademark provided it fulfills the same purpose as a more traditional trademark such as a brand name or a logo: to identify a particular provider. In one much more pedestrian case, the Supreme Court ruled explicitly that Qualitex Co., a maker of dry-cleaning equipment, could “own” a certain puke-green color. In fact there’s a reason all of this makes it into the court documents, and not just the news reports hoping to take what might otherwise be a rather dry intellectual property dispute and sex it up with some boldface names. Louboutins were even the title subject of a terrible-yet-catchy Jennifer Lopez song in which she mentions the red soles alongside her own iconic posterior: I’m throwing on my Louboutins / Watch these red bottoms / And the back of my jeans / Watch me go / Bye baby. ![]() Many of those were on famous feet: the complaint makes so much use of celebrities and models wearing Louboutin’s shoes that it reads in places more like a Page Six item than a legal document.Īnd in fashion’s other, fantasy universe they’re similarly ubiquitous among the-eh, well-heeled: Carrie Bradshaw and Barbie both have pairs in their fictional closets. The legend, and now the lawsuit, has it that almost 20 years ago Louboutin first kicked a pair of shoes up a notch by painting the soles red with nail polish they’ve appeared on every shoe he’s sold in the United States since. Louboutins are well known to fashion gurus, famous for their insanely high heels, fanciful designs, and bright red undersoles. How does all this apply to the Louboutin case? First, some background. How many times has Tim Gunn arched his eyebrows at a “Project Runway” contestant and singsonged that their projects looked awfully similar to some famous designer’s collection or that they need a course in fashion history? Among serious designers, “derivative” is an insult almost worse than “cheap-looking.” Of course blatant copycats don’t have credibility. Fast-moving trends reduce the life cycle of the product so that people feel the need to refresh their wardrobes constantly-and keep the fashion houses in business. When a designer introduces a new trick, if it strikes a chord then every competitor makes their own version and every stylish customer wants it. ![]() Speed, change, and imitation are the hallmarks of the business. This is a realm in which clothes from last season are no longer valuable. Unlike a new drug or pop single, where copies just displace the original and steal away potential customers, much of the copying in fashion fuels the whole industry. Senator Chuck Schumer (disclosure: my former boss) sponsored a bill last year to create a special limited three-year copyright for certain unique fashion designs, and while it had some supporters, others argued persuasively that the lack of fashion protection is a good thing. Patents are for inventions, copyrights for creative works, and fashion traditionally falls outside both definitions. They aren’t usually eligible for patents or copyrights. On the whole, fashion designs get very little intellectual property protection. In fact, I think the law fundamentally supports all three reactions, partly. ![]() ![]() ![]() ![]() Once assumed to be a social media platform that’s just for kids, the TikTok user-base is diversifying fast with brands, influencers, YouTubers, parents, and even grandparents joining the fun. To do this, start the video of simple before it dramatically. freepeople, food52, and rarebeauty TikTok was the most-downloaded app in 2020, surpassing 3 billion downloads. Tutorial original sound - CAPCUT TEMPLATES - CAPCUT TEMPLATES. A strange but up and coming trending sound with only 10K videos underneath this sounds belt. New Trending Audio on tiktok right now, easy to hop on, lip sync the words and add text to the screen #trendingtoday□ #trendingsound #recaptrend2022 #newsound #newsoundalerts⚠️ #fridaytrendsetters #trendingfriday #trendingfridays #trendingaudio2022 #contentgrowth #savvydigital #howtogrowfastontiktok #2022recap #2022recaptrend #soundtrending2022 #soundtrendingtiktok #socialmediatips #businesstrends #contentideasforhandmadebiz #businessowneruk". These are some of my favorite TikTok sounds through 2022 Theres way more but these ones are great. New Trending Audio on tiktok right now, easy to hop on, lip sync the words and add text to the screen #trendingtoday□ #trendingsound #recaptrend2022 #newsound #newsoundalerts⚠️ #fridaytrendsetters #trendingfriday #trendingfridays #trendingaudio2022 #contentgrowth #savvydigital #howtogrowfastontiktok #2022recap #2022recaptrend #soundtrending2022 #soundtrendingtiktok #socialmediatips #businesstrends #contentideasforhandmadebiz #businessownerukĢ50 Likes, TikTok video from Michelle | Digital Marketing "2022 trending recap audio, share your favourite 2022 memories with this audio. Discover videos related to 2022 sounds on TikTok. Navigate to the Discover tab and scroll through the featured videos to see what songs are. 2022 trending recap audio, share your favourite 2022 memories with this audio. Strategy How To Find and Use Business-Friendly TikTok Sounds Add a trending TikTok sound to your video, and you’ll enter into a larger conversation happening around that audio. 6 minutes ago &0183 &32 First, TikToks Discover page is a treasure trove of trending content, including popular music and sounds. ![]() ![]() Excited about these roles because Lena and Nick are playing Julia and Ricky – mom and dad.īoth Paige and myself are 3rd generation performers with a long history in the unique and crazy world of pro wrestling. The brilliant/Bad Ass and another Brit who’s often mistaken as my twin, the genius (Nick Frost). Her and I have talked about this project for years now and we’re all excited to bring her and her family’s story to life.Ĭool casting announcements coming this week!īelow is the documentary about her wrestling family that inspired the film…Ī post shared by therock welcomes to our #FightingWithMyFamily cast these two amazing actors. ![]() Paige and I both know what it’s like to come from a wrestling family who’s had it’s good and hard times. Pleasure to partner with WWE Studios and Film 4 to bring this cool story to life. Merchant, being from the UK, locked in to a strong POV and vision of how gritty and heartfelt this film needs to be and the rest is history. He sent it to my long time ace producer Kevin Misher, who immediately responded to the doc and he thought we should go after one of our favorite writer/directors for material like this, Stephen Merchant. My gut said there was a great movie to be made so I sent to my agent Brad Slater at WME who loved it. That no matter how crazy life gets, no matter how dysfunctional our families can sometimes be and especially regardless of how much we fight – we’re always there for each other when it counts. The family strong element I saw in the doc, is what grabbed my attention. That daughter, is current WWE Women’s Superstar, Paige. Years ago (2012) while shooting Fast & Furious in London, I was up at 3am (too much caffeine) and stumbled upon a documentary on a UK station about a local wrestling family and their daughter’s unlikely journey into the global spotlight. Then eventually, I can do the entrance for her and while its going not going to be 100% accurate since 2006, it'll at least be an honest attempt on my end to finishing what my man in the past started by making the CAW.A post shared by therock Our is excited to announce production on a cool project we’ve been working on for years based on a very unique and gritty professional wrestling family and a their daughter’s journey into the spotlight of the WWE. Unfortunately, the game can't replicate PTO or the RamPaige, so the Spinning Fisherman Suplex (Paige-Turner) and Steven Kick (SuperKick) will probably be the closest things we can get for her finishers.īut.as far as her main move-set, I have to admit, I'm not sure where to start, and if anyone more experienced with movesets could help me, I'd be most grateful. ![]() (Plus Chick Kick is highly used already for a lot of Diva Caws and I didn't want to repeat the same finishers) I also had an idea to use the Steven Kick as her (SuperKick) since that more closely follows her kicks from youtube videos I've seen. I've already figured out her finisher at least, her Paige-Turner was easily substituted with the Spinning Fisherman Suplex which looks closely 80% similar to it, so I used that for both slots. ![]() I created her recently using the formula posted here (Shoutouts to this man as he pulled this off almost perfectly and I only made minor outfit edits) So hey, would anyone be willing to help me divise the main moveset for Paige? ![]() ![]() ![]() ![]() The finale of season 2 left many of Euphoria’s most interesting storylines unfinished or unanswered, including Ashtray’s death and Fezco’s arrest, Rue and Jules officially breaking up, Nate sending Cal to jail, and Rue still owing Laurie thousands of dollars. Euphoria season 2 had far more drama than season 1, and showrunner Sam Levinson is letting viewers know that the madness will only increase in Euphoria season 3. Maddy saying “ this is just the beginning” is also an apt summary of how Euphoria will progress in its future seasons. Nate breaking up with Cassie before interrupting Lexi’s play may have seemed bad, but Maddy knows that’s just child’s play compared to what he’ll do later on. Considering Cassie had already turned into a clone of Maddy before the end of Euphoria season 2, Maddy has clearly already recognized that Nate is repeating his abusive patterns on her former best friend. In a dream had by Nate in Euphoria season 2 episode 7, he imagined Cassie telling him that he could control her in any way he wants, including her clothes, who she speaks to, and where she goes. Maddy went through hell when she dated Nate and, to make it worse, Cassie knew every detail of what she went through and still chose to pursue a relationship with him. The meaning of Maddy’s last line in Euphoria season 2 is primarily geared at warning Cassie of how much more abusive, volatile, and controlling Nate will be to her. Related: Who's The Third Kid In The Jacobs Family Photo? Why Has Euphoria Ignored Him? In Euphoria’s season 2 finale, Cassie tells Maddy that Nate broke up with her before she went on stage and ruined Lexi’s play, with Maddy responding, “ Don’t worry. Maddy, knowing how emotionally and often physically abusive Nate was, said Cassie could have him, which was soon followed by Nate pointing a gun at her to get back the tape of Cal and Jules. ![]() Maddy’s idea to get back with Nate came to a full stop when Zendaya’s character Rue exposed Cassie and Nate's secret affair, with Maddy feeling particularly betrayed by Cassie. ![]() Want to see where the students of East Highland get it all wrong? As we wait for the final episode to drop, we round up the Euphoria sex and relationship plotlines from season two that will have you wishing that their high school had a relationship therapist on staff.Alexa Demie’s character often recognized the abusive nature of her relationship with Nate but still felt that it may have been easier to fall back with him. If anything, Euphoria could serve as a cautionary tale of how not to run your love life, rather than offer up any examples of model behaviour. And it's especially worth keeping in mind that the series has never made much of a claim to being realistic (we definitely didn't have the budget to be wearing Miu Miu to Maths class when we were 16.). However, it's important to remember that the show is a work of fiction, so everything we see on screen in Euphoria really should be taken with a pinch of salt. And while the first series was praised for its matter-of-fact look at sexual fluidity, particularly through its depiction of Rue and Jules' (aka "Rules") blossoming romance, we witness this relationship quickly crumble and fall into a tangle of lies and cheating in season two. And while the show's quotable dialogue and Y2K fashion have been widely praised, Euphoria's sex scenes and relationships have opened the series to criticism.Ĭoming under fire for romanticising self-destructive behaviour (particularly when it comes to alcohol and drug abuse) and aestheticising trauma, the Euphoria universe sometimes sees toxic relationships framed as "true love" – at least in the eyes of its adolescent protagonists. If you’re anything like us, you’ve been eagerly following Euphoria each week: shipping Fexi, reliving every episode through memes and replicating the show’s iconique looks. ![]() ![]() ![]() ![]() A Superglide needs a jump input first and then a crouch input 1 frame later. Always disable your anti virus before extracting the game to prevent it from deleting the crack files. Apex Legends Superglide Trainer superglidetrainer logo. For now its still on the early access stage and still have a lot of improvements but I think this aim trainer has a. Also, be sure to right click the exe and always select “Run as administrator” if you’re having problems saving the game. Apex Aim Trainer is the first aim trainer for Apex Legends game. Look for a ‘HOW TO RUN GAME!!.txt’ file for more help. You need these programs for the game to run. If you get any missing dll errors, make sure to look for a _Redist or _CommonRedist folder and install directx, vcredist and all other programs in that folder. NOTICE: This game is already pre-installed for you, meaning you don’t have to install it. Don't forget to run the game as administrator. Apex Legends - Bangalore Edition DLC Origin CD Key. Have fun and play! Make sure to run the game as administrator and if you get any missing dll errors, look for a Redist or _CommonRedist folder and install all the programs in the folder.Ĭlick the download button below to start Apex Aim Trainer Free Download with direct link. The goal of KovaaKs FPS Aim Trainer is to enable players to create their own training with realistic.Double click inside the Apex Aim Trainer folder and run the exe application.zip file and click on “Extract to Apex Aim Trainer” (To do this you must have 7-Zip, which you can get here). Once Apex Aim Trainer is done downloading, right click the.for first-person shooting games like CS GO, Fortnite, or Apex Legends. ![]() Now let the download begin and wait for it to finish. Aimtastic is a free-to-play aim training game available on steam and its updated. Wait 5 seconds and click on the blue ‘download now’ button.Click the Download button below and you should be redirected to UploadHaven.How to Download & Install Apex Aim Trainer The most effective practice is the train LTM while its up. It doesnt match up precisely with the mechanics of apex, and because it doesnt, you’ll end up getting better at the aim trainer and it wont really convert to in-game skill unless target reading is your problem. * Customizeable bot behavior, including movement type (stand still, strafe, follow, etc.), speed, etc. Apex aim trainer honestly isn’t a great tool. It is extremely useful for practicing long range snipping. * Aim Assistant indicates the position of a perfect leading shot. * Provide with weapon attachments and optics. The game does have a built-in aim tracking course, something that KovaaK sells as paid downloadable content. As a result, it has less content to train with. This is an aim training program to help you improve your shooting skills in Apex Legends.įeatures: * Real game FOV and mouse sensitivity settings * Provide with weapons similar to the real game. KovaaK 2.0 Aim Lab is an early access title that’s much newer than KovaaK. ![]() ![]() ![]() However, he is better known by his nomen, or personal name. When transliterated, the name is mn-pḥty-rʿ, which is usually interpreted as Menpehtyre, meaning "Established by the strength of Ra". Upon his accession, Ramesses assumed a prenomen, or royal name. Since Horemheb had no surviving children, he ultimately chose Ramesses to be his heir in the final years of his reign presumably because Ramesses I was both an able administrator and had a son (Seti I) and a grandson (the future Ramesses II) to succeed him and thus avoid any succession difficulties. Horemheb himself had been a nobleman from outside the immediate royal family, who rose through the ranks of the Egyptian army to serve as the royal advisor to Tutankhamun and Ay and, ultimately, pharaoh. Ramesses also served as the High Priest of Set – as such, he would have played an important role in the restoration of the old religion following the Amarna heresy of a generation earlier, under Akhenaten. Ramesses I found favor with Horemheb, the last pharaoh of the tumultuous Eighteenth Dynasty, who appointed the former as his vizier. This shows the high status of Ramesses' family. His uncle Khaemwaset, an army officer, married Tamwadjesy, the matron of Tutankhamun's Harem of Amun, who was a relative of Huy, the viceroy of Kush, an important state post. He was a son of a troop commander called Seti. Originally called Pa-ra-mes-su, Ramesses I was of non-royal birth, being born into a noble military family from the Nile Delta region, perhaps near the former Hyksos capital of Avaris. ![]() Pharaoh Ramses I making an offering before Osiris, Allard Pierson Museum. ![]() ![]() ![]() ![]() David A Lorenz Regional Park (DALRP) South. 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